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Review and meta-analysis found that prenatal folic acid was associated with a 58% reduction in autism but had no effect on mental and motor development.

Lucia IglesiasJosefa CanalsVictoria Arija
Published in: Acta paediatrica (Oslo, Norway : 1992) (2018)
Although the results should be interpreted with caution, they showed that routine prenatal supplements of folic acid were associated with significantly lower levels of ASD. Further studies are needed to reach a firm conclusion, given the multifactorial aetiology of neurodevelopment.
Keyphrases
  • autism spectrum disorder
  • pregnant women
  • intellectual disability
  • attention deficit hyperactivity disorder
  • mental health
  • clinical practice
  • working memory