Preoperative sarcopenia is associated with poor overall survival in pancreatic cancer patients following pancreaticoduodenectomy.
Yan-Chih PengChien-Hui WuYu-Wen TienTzu-Pin LuYu-Hsin WangBang-Bin ChenPublished in: European radiology (2020)
• Sarcopenia and sarcopenic obesity can be evaluated by abdominal CT on L3 level. • Patients with diabetes mellitus (DM) had lower sex-standardized subcutaneous adipose tissue area index and skeletal muscle density and higher visceral to subcutaneous adipose tissue area ratio than did those without DM. • Preoperative sarcopenia, sarcopenic obesity, and new-onset diabetes mellitus may predict poor overall survival in pancreatic cancer patients following pancreaticoduodenectomy.
Keyphrases
- insulin resistance
- skeletal muscle
- adipose tissue
- glycemic control
- high fat diet
- high fat diet induced
- metabolic syndrome
- end stage renal disease
- type diabetes
- weight loss
- patients undergoing
- chronic kidney disease
- newly diagnosed
- ejection fraction
- prognostic factors
- weight gain
- community dwelling
- free survival
- positron emission tomography