High-phosphate diet causes atrial remodeling and increases atrial fibrillation vulnerability via STAT3/NF-κB signaling and oxidative stress.
Yu-Juei HsuGwo-Jyh ChangYing-Ju LaiYi-Hsin ChanWei-Jan ChenChi-Tai KuoYung-Hsin YehPublished in: Acta physiologica (Oxford, England) (2023)
High-Pi intake causes atrial structural and electrical remodeling and increases AF vulnerability, which is mediated through STAT3/NF-κB signaling and oxidative stress. High dietary Pi intake can exert detrimental effects on atria and may increase AF risk.
Keyphrases
- atrial fibrillation
- oxidative stress
- catheter ablation
- left atrial
- signaling pathway
- oral anticoagulants
- climate change
- left atrial appendage
- cell proliferation
- dna damage
- lps induced
- heart failure
- direct oral anticoagulants
- pi k akt
- diabetic rats
- nuclear factor
- physical activity
- weight loss
- weight gain
- toll like receptor
- venous thromboembolism