Rapid viral rebound after analytical treatment interruption in patients with very small HIV reservoir and minimal on-going viral transcription.

Pieter PannusSofie RutsaertStéphane De WitSabine D AllardGuido VanhamBasiel ColeCoca NescoiJoeri AertsWard De SpiegelaereAchilleas TsoumanisMarie-Madeleine CouttenyeNatacha HerssensMarie-Angélique De ScheerderLinos VandekerckhoveEric Florence

Published in: Journal of the International AIDS Society (2020)

The combination of low levels of t-DNA and US-RNA in PBMCs, corresponding respectively to a small and transcriptionally silent viral reservoir, is not predictive of viral remission after TI in patients on ART.

Keyphrases

sars cov
end stage renal disease
antiretroviral therapy
hiv infected
ejection fraction
chronic kidney disease
newly diagnosed
human immunodeficiency virus
hiv positive
prognostic factors
transcription factor
circulating tumor
rheumatoid arthritis
hiv aids
disease activity
nucleic acid
cell free
patient reported