Secreted protein acidic and rich in cysteine (SPARC) knockout mice have greater outflow facility.

Ling YuYuxi ZhengBrian J LiuMin Hyung KangJ Cameron MillarDouglas J Rhee

Published in: PloS one (2020)

The lower IOP of SPARC -/- mice is due to greater aqueous humor outflow facility through the conventional pathway. Corresponding changes in several matricellular proteins and ECM structural components were noted in the TM of SPARC -/- mice.

Keyphrases

high fat diet induced
ionic liquid
long term care
type diabetes
wild type
insulin resistance