So far, yet so close: α-Catenin dimers help migrating cells get together.

Published in: The Journal of cell biology (2017)

Epithelial cells in tissues use their actin cytoskeletons to stick together, whereas unattached cells make active plasma membrane protrusions to migrate. In this issue, Wood et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201612006) show that the junction component α-catenin is critical in freely moving cells to promote adhesion and migration.

Keyphrases

induced apoptosis
cell cycle arrest
cell proliferation
oxidative stress
cell death
mesenchymal stem cells
escherichia coli
bone marrow
cell therapy
pseudomonas aeruginosa
cystic fibrosis
candida albicans