Profiling the microRNA signature of the peripheral sensory ganglia in experimental autoimmune encephalomyelitis (EAE).
Timothy N FriedmanMuhammad Saad YousufAna CatuneanuMansi DesaiCamille A JuźwikAlyson E FournierBradley J KerrPublished in: Journal of neuroinflammation (2019)
This study provides evidence that females are uniquely affected by MOG35-55-EAE and that this difference may result from additional signaling not present in the male. The altered transcriptome of females correlates with other studies finding hyperactivity of pain-sensing neurons and suggests underlying sex-specific pathways for neuropathic pain.