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Morphometric analysis of alpha-1, 3-galactosyltransferase knockout pig kidney and heart.

Bala Murali Krishna VasamsettiSang Hyoun ParkHarikrishna Reddy RallabandiHeasun LeeSung-June ByunSun A OckHwi-Cheul LeeSeongsoo HwangKeon Bong Oh
Published in: Laboratory animals (2020)
We report a morphometric evaluation of α1,3-galactosyltransferase knockout (GTKO) pig heart and kidney (n = 9) at the end of one, three and seven months. Organs parameters gradually increased with the age (p < 0.05) and body weight (p < 0.05) of the pigs. Organs morphometries were significantly correlated to the age and body weight of the animal. We were able to conclude the average size of GTKO pig heart and kidney based on age and body weight, which could be helpful in estimating the size of these organs non-invasively for transplantation.
Keyphrases
  • body weight
  • heart failure
  • atrial fibrillation