Racial and Sex Differences in Genomic Profiling of Intrahepatic Cholangiocarcinoma.

Diamantis I TsilimigrasHunter SteckoIoannis Ntanasis-StathopoulosTimothy M Pawlik

Published in: Annals of surgical oncology (2024)

Distinct genomic variations exist in iCCA across race and sex. Differences in mutational profiles of iCCA patients highlight the importance of including a diverse patient population in iCCA clinical trials as well as the importance of recognizing different genetic drivers that may be targetable to treat distinct patient cohorts.

Keyphrases

clinical trial
copy number
case report
end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
single cell
patient reported outcomes
gene expression
african american
patient reported
phase iii