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Odontoblast cell death induces NLRP3 inflammasome-dependent sterile inflammation and regulates dental pulp cell migration, proliferation and differentiation.

B Al NatourFionnuala T LundyP N MoynahImad AboutC JeanneauC R IrwinY DomberoskiIkhlas A El-Karim
Published in: International endodontic journal (2021)
Dead odontoblasts induced NLRP3 inflammasome-dependent sterile inflammation and activated the migration, proliferation and differentiation of DPCs.
Keyphrases
  • nlrp inflammasome
  • cell migration
  • cell death
  • oxidative stress
  • signaling pathway
  • diabetic rats
  • high glucose
  • drug induced
  • cell proliferation
  • endothelial cells
  • pi k akt