Early-Life Gut Microbiome-The Importance of Maternal and Infant Factors in Its Establishment.
Fatemeh Ramezani KapourchaliGail A M CresciPublished in: Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition (2020)
The early-life microbiome is gaining appreciation as a major influencer in human development and long-term health. Multiple factors are known to influence the initial colonization, development, and function of the neonatal gut microbiome. In addition, alterations in early-life gut microbial composition is associated with several chronic health conditions such as obesity, asthma, and allergies. In this review, we focus on both maternal and infant factors known to influence early-life gut colonization. Also reviewed is the important role of infant feeding, including evidence-based strategies for maternal and infant supplementation with the goal to protect and/or restore the infant gut microbiome.
Keyphrases
- early life
- healthcare
- public health
- birth weight
- mental health
- endothelial cells
- pregnancy outcomes
- metabolic syndrome
- chronic obstructive pulmonary disease
- type diabetes
- insulin resistance
- health information
- weight gain
- weight loss
- microbial community
- pregnant women
- risk assessment
- physical activity
- induced pluripotent stem cells
- high fat diet induced