High-grade salivary gland cancer: is surgery followed by radiotherapy an adequate treatment to reach tumor control? Results from a tertiary referral centre focussing on incidence and management of distant metastases.
Viola FreitagSebastian LettmaierSabine SemrauMarkus HechtKonstantinos MantsopoulosSarina K MüllerMaximillian TraxdorfHeinrich IroAbbas AgaimyRainer FietkauMarlen HaderleinPublished in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2021)
With surgery and radio-chemotherapy, a high rate of loco-regional control is reached, but over 40% of patients develop distant metastases in the further follow-up which usually present a diffuse pattern involving in a diffuse metastases. Therefore, in the future, intensified interdisciplinary combination therapies even in the first-line treatment in certain subtypes of high-grade SGC should be investigated.
Keyphrases
- high grade
- low grade
- minimally invasive
- end stage renal disease
- coronary artery bypass
- lymph node
- ejection fraction
- newly diagnosed
- chronic kidney disease
- locally advanced
- primary care
- risk factors
- radiation therapy
- peritoneal dialysis
- papillary thyroid
- squamous cell carcinoma
- acute coronary syndrome
- squamous cell
- young adults
- atomic force microscopy
- atrial fibrillation
- combination therapy
- patient reported