The impact of dietary fermentable carbohydrates on a postinflammatory model of irritable bowel syndrome.
Caroline J TuckAlberto CamineroNestor N Jiménez VargasCarmen L SoltysJosue O Jaramillo PolancoCintya D Lopez LopezMarco ConstanteSandra R LourenssenElena F VerduJane G MuirAlan E LomaxDavid E ReedStephen J VannerPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2019)
In this preclinical study, reducing dietary FODMAPs did not exacerbate nor mitigate inflammation. Microbiota profile changes were largely driven by inflammation rather than diet. Low FODMAP intake caused a shift toward proteolytic fermentation following inflammation.