Investigating the epigenetic profile of the inflammatory gene IL-6 in late-life depression.

Joanne RyanLauren PilkingtonKatharina NeuhausKaren RitchieMarie-Laure AncelinRichard Saffery

Published in: BMC psychiatry (2017)

This study presents evidence that IL6 methylation may be a marker of depression status in older individuals, however further work is now needed to replicate these findings and to assess the association with inflammatory status of individuals.

Keyphrases

depressive symptoms
dna methylation
genome wide
oxidative stress
sleep quality
gene expression
physical activity
copy number
community dwelling