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Investigating the epigenetic profile of the inflammatory gene IL-6 in late-life depression.

Joanne RyanLauren PilkingtonKatharina NeuhausKaren RitchieMarie-Laure AncelinRichard Saffery
Published in: BMC psychiatry (2017)
This study presents evidence that IL6 methylation may be a marker of depression status in older individuals, however further work is now needed to replicate these findings and to assess the association with inflammatory status of individuals.
Keyphrases
  • depressive symptoms
  • dna methylation
  • genome wide
  • oxidative stress
  • sleep quality
  • gene expression
  • physical activity
  • copy number
  • community dwelling