Impact of biologic therapies and small molecules on the risk of major adverse cardiovascular events in patients with inflammatory bowel diseases: Systematic review and meta-analysis of randomised controlled trials.

Mohammad ShehabAfrah AlkazemiFatema AlrashedPeter LakatosTalat Bessissow

Published in: Expert review of gastroenterology & hepatology (2023)

The use of biologic therapies and small molecules among adult patients with IBD had no significant impact on the risk of MACEs during induction and maintenance period of RCTs. Real world data is warranted to asses long term risks.

Keyphrases

cardiovascular events
rheumatoid arthritis
coronary artery disease
cardiovascular disease
electronic health record
big data
human health
emergency department
machine learning
risk assessment
ulcerative colitis
adverse drug
deep learning