Aotearoa New Zealand Māori and Pacific Population-amplified Gout Risk Variants: CLNK Is a Separate Risk Gene at the SLC2A9 Locus.

Aichang JiAmara ShaukatRiku TakeiMatthew BixleyMurray CadzowRuth K ToplessTanya J MajorAmanda Phipps-GreenMarilyn E MerrimanJennie Harré HindmarshLisa K StampNicola DalbethChanggui LiTony Raymond Merriman

Published in: The Journal of rheumatology (2021)

We provide nominal evidence for the existence of population-amplified genetic variants conferring risk of gout in Polynesian populations. Polymorphisms in CLNK have previously been associated with gout in other populations, supporting our evidence for the association of this gene with gout.

Keyphrases

uric acid
copy number
genome wide
metabolic syndrome
genome wide identification
dna methylation
breast cancer risk