A randomized controlled study of neoadjuvant metformin with chemotherapy in nondiabetic breast cancer women: The METNEO study.

Manar A Serageldin Noha A El-BassiounyYasser El-KermRania Gaber Aly Maged Wasfy Helmy Mahmoud M El-Mas Amira Bisher Kassem

Published in: British journal of clinical pharmacology (2024)

Metformin improves clinical and pathological responses to neoadjuvant AC-T chemotherapy in BC via prompting directionally opposite changes in DRs (increments) and CD133 + (decrements) expressions. This study was registered in ClinicalTrials.gov (registration number: NCT04170465, https://clinicaltrials.gov/ct2/show/NCT04170465).

Keyphrases

locally advanced
rectal cancer
lymph node
type diabetes
polycystic ovary syndrome
magnetic resonance
adipose tissue
metabolic syndrome