Safety and Homing of Human Dental Pulp Stromal Cells in Head and Neck Cancer.
Greet MerckxMelissa Lo MonacoIvo LambrichtsUwe HimmelreichAnnelies BronckaersEsther WolfsPublished in: Stem cell reviews and reports (2021)
Our research suggests that intratumourally delivered DPSCs might be used as safe factories for the continuous delivery of anti-cancer drugs in HNC. Nevertheless, further optimization as well as efficacy studies are necessary to understand and improve in vivo tumour homing and determine the optimal experimental set-up of stem cell-based cancer therapies, including dosing and timing.