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Liver-derived extracellular vesicles from patients with hepatitis B virus-related acute-on-chronic liver failure impair hepatic regeneration by inhibiting on FGFR2 signaling via miR-218-5p.

Senquan ZhangJie YuKeqiang RaoJie CaoLijie MaYeping YuZhe LiZhaokai ZengYongbing QianMo ChenHua Lian Hang
Published in: Hepatology international (2023)
The current data reveal the mechanism underlying impaired liver regeneration in HBV-ACLF that promotes the discovery of new therapeutic approaches.
Keyphrases
  • liver failure
  • hepatitis b virus
  • stem cells
  • small molecule
  • signaling pathway
  • genome wide
  • electronic health record
  • big data
  • high throughput
  • wound healing
  • dna methylation
  • data analysis
  • mechanical ventilation