A Reference Range of Hydroxychloroquine Blood Levels that Can Reduce Odds of Active Lupus and Prevent Flares.

An effective reference range of HCQ blood levels, 750-1200 ng/ml, was associated with 71% lower odds of active lupus, and maintaining levels within this range reduced odds of flares by 26%. These findings could guide clinicians to individualize HCQ doses to maintain HCQ levels within this range to maximize efficacy. This article is protected by copyright. All rights reserved.