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Structural basis for inactivation of PRC2 by G-quadruplex RNA.

Jiarui SongAnne R GoodingWayne O HemphillVignesh KasinathThomas R Cech
Published in: bioRxiv : the preprint server for biology (2023)
Cryo-EM structure of RNA-bound PRC2 dimer elucidates an unexpected mechanism of PRC2 inhibition by RNA.
Keyphrases
  • structural basis
  • nucleic acid