Fluorescence-tagged salivary small extracellular vesicles as a nanotool in early diagnosis of Parkinson's disease.

Simran RastogiKomal RaniSanskriti RaiRishabh SinghPrahalad Singh BhartiVaibhav SharmaJyoti SahuVrinda KapoorPoorvi VishwakarmaSumit GargShivajirao Lahu GholapKrishna Kishore InampudiGyan Prakash ModiNeerja RaniMadhavi TripathiAchal SrivastavaRoopa RajanFredrik NikolajeffSaroj Kumar

Published in: BMC medicine (2023)

In this study, for the first time, we have found that the fluorescence-tagged sEV has the potential to screen the progression of disease with clinically acceptable sensitivity and can be a potent early detection method for PD.

Keyphrases

high throughput
energy transfer
risk assessment
anti inflammatory
single cell