Rapid identification of chemical compositions of three species of Schisandra chinensis by ultra-high-performance liquid chromatography quadrupole-orbitrap-mass spectrometry.
Lexin ShuHuixin QiuShumin ZhangJing XueSitong LiuJun QianSiyue ChenYanyan XuYu-Bo LiPublished in: Journal of separation science (2023)
Schisandra chinensis is a traditional Chinese medicine, which has played an important role in the field of medicine and food. In this study, ultra-high-performance liquid chromatography quadrupole-orbitrap-mass spectrometry was used to rapidly classify and identify the chemical compositions. Note that 32, 28, and 30 kinds of compounds were successfully identified from northern Schisandra chinensis, vinegar-processed Schisandra chinensis, and wine-processed Schisandra chinensis, respectively. The cleavage patterns of various components including lignans, organic acids, flavonoids, and terpenoids were summarized, and the effects of different processing methods on Schisandra chinensis were analyzed through chemical composition. This method realized the rapid classification and identification of raw Schisandra chinensis and two different processed products, and provided references for improving the traditional processing methods, strengthening quality control, and ensuring safe clinical application.
Keyphrases
- tandem mass spectrometry
- ultra high performance liquid chromatography
- liquid chromatography
- mass spectrometry
- high resolution mass spectrometry
- gas chromatography
- high performance liquid chromatography
- simultaneous determination
- high resolution
- solid phase extraction
- quality control
- machine learning
- ms ms
- transcription factor
- risk assessment
- sensitive detection