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Fumagillin regulates stemness and malignancies in cancer stem-like cells derived from liver cancer via targeting to MetAP-2.

Ke ZhangJian HuZi-Yi Zhao
Published in: PloS one (2023)
This work offers evidence for fumagillin as a specific inhibitor of liver cancer CSCs and proposes a novel strategy for cancer therapy.
Keyphrases
  • cancer therapy
  • drug delivery
  • papillary thyroid
  • cancer stem cells
  • stem cells
  • squamous cell
  • epithelial mesenchymal transition
  • lymph node metastasis
  • childhood cancer
  • young adults
  • signaling pathway