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The role of aging in cancer.

Aaron HavasShanshan YinPeter D Adams
Published in: Molecular oncology (2022)
Many cancers show an increase in incidence with age, and age is the biggest single risk factor for many cancers. However, the molecular basis of this relationship is poorly understood. Through a collection of review articles, our thematic issue discusses the link between aging and cancer in aspects including somatic mutations, proteostasis, mitochondria, metabolism, senescence, epigenetic regulation, immune regulation, DNA damage, and telomere function.
Keyphrases
  • dna damage
  • papillary thyroid
  • squamous cell
  • childhood cancer
  • oxidative stress
  • lymph node metastasis
  • endothelial cells
  • young adults
  • squamous cell carcinoma
  • dna methylation
  • genome wide