Nur77 Deficiency Exacerbates Macrophage NLRP3 Inflammasome-Mediated Inflammation and Accelerates Atherosclerosis.
Ruosen YuanWei-Feng ZhangPeng NieKeke LanXiaoxiao YangAnwen YinQingqing XiaoYejiao ShenKe XuBen HeXin PanLing-Hong ShenBen HePublished in: Oxidative medicine and cellular longevity (2022)
This study demonstrated that Nur77 deletion promotes atherogenesis by exacerbating NLRP3 inflammasome-mediated inflammation.