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Nur77 Deficiency Exacerbates Macrophage NLRP3 Inflammasome-Mediated Inflammation and Accelerates Atherosclerosis.

Ruosen YuanWei-Feng ZhangPeng NieKeke LanXiaoxiao YangAnwen YinQingqing XiaoYejiao ShenKe XuBen HeXin PanLing-Hong ShenBen He
Published in: Oxidative medicine and cellular longevity (2022)
This study demonstrated that Nur77 deletion promotes atherogenesis by exacerbating NLRP3 inflammasome-mediated inflammation.
Keyphrases
  • nlrp inflammasome
  • oxidative stress
  • cardiovascular disease
  • adipose tissue
  • type diabetes