Login / Signup

Amelanotic/hypomelanotic lentigo maligna: Dermoscopic and confocal features predicting diagnosis.

Maria Antonietta PizzichettaJerry PoleselJean L PerrotPietro RubegniDiletta FioraniArianna RizzoIgnazio StanganelliSerena MagiLaura MazzoniMatelda MedriMichele M DominiciFederica ToffoluttiFrancesca FarnetaniNicola LippolisGioia PedroniSilvana CiardoAlessandra G CondorelliConforti ClaudioGiovanni PellacaniIris ZalaudekFabio PuglisiElisa Cinottinull null
Published in: Journal of the European Academy of Dermatology and Venereology : JEADV (2022)
Amelanotic/hypomelanotic lentigo maligna and lentigo maligna melanoma may have the same dermoscopic features of AHM on other body sites, such as milky red areas, peripheral light brown structureless areas and linear irregular vessels. These features, asymmetric pigmented follicles and at RCM ≥ 3 atypical cells in five fields and focal follicular extension of atypical cells at DEJ may help in recognizing AHLM/LMM even when LM conventional features (e.g., obliteration of hair follicles under dermoscopy and large pagetoid cells under RCM) are absent or present only in very small areas of the lesion.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • endoplasmic reticulum stress
  • cell death
  • oxidative stress
  • solid state