IL-10 to TNFα ratios throughout early first trimester can discriminate healthy pregnancies from pregnancy losses.

Janina KaislasuoSamantha SimpsonJesper F PetersenGang PengPaulomi AldoEllen LokkegaardMichale PaidasLubna PalSeth Guller Gil Mor

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2019)

We provide evidences of differences in early immunomodulation in healthy pregnancies vs those destined to end in first-trimester loss. The ratio of IL-10 to TNFα rises significantly higher in viable pregnancies as early as 4.5 weeks compared to pregnancies loss.

Keyphrases

preterm birth
gestational age
pregnancy outcomes
rheumatoid arthritis
pregnant women