Changes in the Fungal Marker β-D-Glucan After Antiretroviral Therapy and Association With Adiposity.
Sahera Dirajlal-FargoCarlee MoserKatherine RodriguezVanessa El-KamariNicholas T FunderburgEmily BowmanTodd T BrownPeter W HuntJudith CurrierGrace A McComseyPublished in: Open forum infectious diseases (2019)
In treatment-naïve participants initiating antiretroviral therapy (ART) with TDF/FTC and either RAL or ATV/r, DRV/r, BDG, a marker of fungal translocation, increased similarly in all arms over 96 weeks. This may represent continued intestinal damage during ART and resulting fungal translocation. Higher BDG was associated with larger fat gains on ART.