Pik3ip1 Is a Negative Immune Regulator that Inhibits Antitumor T-Cell Immunity.

Yichen ChenJun WangXinye LiJingjing SongJuan FangXiangqi LiuTao LiuQunxing LiShuqiong WenDa MaJuan XiaLiqun LuoSong Guo ZhengJun CuiGucheng ZengLieping ChenBin Cheng

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)

Our data reveal a critical role for Pik3ip1 as a novel inhibitory immune regulator of T-cell responses and provide a potential molecular target for cancer immunotherapy.

Keyphrases

transcription factor
electronic health record
genome wide
big data
single cell
human health
dna methylation
risk assessment
single molecule
artificial intelligence
deep learning