Maternal cell contamination in embryonic chromosome analysis of missed abortions.
Nozomi OuchiToshiyuki TakeshitaSayuri KasanoRyoko YokoteMirei YonezawaRyuhei KurashinaTomoko IchikawaIkuno KawabataYoshimitsu KuwabaraShunji SuzukiPublished in: The journal of obstetrics and gynaecology research (2022)
We found maternal cell contamination in 15% of all the cases. Moreover, in many cases of the normal female karyotype, it was suspected that only maternal chromosomes were cultured. When performing embryonic chromosome analysis in recurrent miscarriages, we should pay attention to maternal cell contamination and interpret the results accordingly.