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Dose equivalence between metaraminol and norepinephrine in critical care.

Arwa Abu SardanehShruti GoradiaSujita W NarayanJonathan PenmAndrew J McLachlanAsad E Patanwala
Published in: British journal of clinical pharmacology (2021)
A conversion dose ratio of 10:1 (metaraminol μg.kg-1 .min-1 :norepinephrine μg.kg-1 .min-1 ) may be used in critically ill patients with shock to account for ease of calculations and variability of the conversion ratio in the primary and sensitivity analyses.
Keyphrases
  • molecular dynamics
  • density functional theory
  • molecular dynamics simulations