Analysis of the HNF4A isoform-regulated transcriptome identifies CCL15 as a downstream target in gastric carcinogenesis.

Zhen NiWenquan LuQi LiChuan HanTing YuanNina SunYong Quan Shi

Published in: Cancer biology & medicine (2021)

P1-HNF4A was the main oncogene during GC progression. The cytokine-cytokine receptor interaction pathway played a pivotal role and may be a promising therapeutic target.

Keyphrases

genome wide
nuclear factor
gene expression
rna seq
single cell
transcription factor
dna methylation
toll like receptor
gas chromatography
mass spectrometry
inflammatory response
immune response