Interpretation of Epidermal Growth Factor Receptor Status in Microscopic Tumor-Free Surgical Margins and Lymph Nodes in Patients with Oral Squamous Cell Carcinoma: An Analysis of 125 Margins.
Mohammad AkheelAshmi WadhwaniaVinay VenkataramuMukhallat QaziTanvi VijayMeharunneesa Aboobacker SidheeqPublished in: Journal of maxillofacial and oral surgery (2024)
This cohort study concludes that EGFR is an important prognostic marker and must be analysed in all microscopic tumour-free margins and lymph nodes in advanced oral squamous cell carcinomas to predict the local recurrences affecting the survival of the patients and the need for addition of anti-EGFR agents in adjuvant treatment. Since the sample size is small, large scale studied must be done to validate the need for adding anti-EGFR agents in adjuvant treatment to improve the survival of patients.
Keyphrases
- epidermal growth factor receptor
- lymph node
- tyrosine kinase
- small cell lung cancer
- end stage renal disease
- ejection fraction
- chronic kidney disease
- advanced non small cell lung cancer
- early stage
- prognostic factors
- squamous cell
- patient reported outcomes
- combination therapy
- free survival
- neoadjuvant chemotherapy
- rectal cancer
- locally advanced