Extracellular Vesicles Derived circSH3PXD2A Inhibits Chemoresistance of Small Cell Lung Cancer by miR-375-3p/YAP1.

Fengmei ChaoYang ZhangLei LvYaqin WeiXiaoyan DouNa ChangQiyi YiMing Li

Published in: International journal of nanomedicine (2023)

Our results manifest that EVs-derived circSH3PXD2A inhibits the chemoresistance of SCLC through miR-375-3p/YAP1 axis. Moreover, EVs-derived circSH3PXD2A may serve as a predictive biomarker for DDP-resistant SCLC patients.

Keyphrases

small cell lung cancer
end stage renal disease
ejection fraction
newly diagnosed
peritoneal dialysis