Analytical methods for assessing changes induced by gamma exposure in an animal model.
Matheus F Soares MingoteTarcísio P R CamposRodinei AugustiGeovanni Dantas CassaliPublished in: Revista da Associacao Medica Brasileira (1992) (2021)
No early radio induced histological or mass weight changes in the radiation exposed rats could be observed at 5 Gy. However, early changes in the molecular level were observed in the DESI-MSI images of the brain lipids. The DESI-MSI method proved to be efficient and relevant, allowing a regional molecular analysis of the tissues, expanding a new field of study that is still in its infancy: radiometabolomics.