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Advanced Quantitative MRI Unveils Microstructural Thalamic Changes Reflecting Disease Progression in Multiple Sclerosis.

Alessandro CagolMario Ocampo-PinedaPo-Jui LuMatthias WeigelMuhamed BarakovicLester Melie-GarcíaXinjie ChenAntoine LuttiEmilia J SitekJens KuhleLudwig KapposMaria Pia SormaniCristina Granziera
Published in: Neurology(R) neuroimmunology & neuroinflammation (2024)
These findings offer deeper insights into thalamic pathology in PwMS, emphasizing the clinical relevance of thalamic damage and its link to disease progression. Advanced qMRI biomarkers show promising potential in guiding interventions aimed at mitigating thalamic neurodegenerative processes.
Keyphrases
  • deep brain stimulation
  • multiple sclerosis
  • white matter
  • magnetic resonance imaging
  • oxidative stress
  • physical activity
  • high resolution
  • magnetic resonance
  • mass spectrometry
  • diffusion weighted imaging