Polypharmacy and Incident Frailty in a Longitudinal Community-Based Cohort Study.

Shahar ShmuelJennifer L LundCarolina AlvarezChristine D HsuPriya PaltaAnna Kucharska-NewtonJoanne M JordanAmanda E NelsonYvonne M Golightly

Published in: Journal of the American Geriatrics Society (2019)

Consistent with the current weight of evidence, our results suggest an association between polypharmacy and incident frailty. Prospective studies evaluating deprescribing interventions are needed to clarify whether reducing polypharmacy decreases frailty incidence. J Am Geriatr Soc 67:2482-2489, 2019.

Keyphrases

community dwelling
cardiovascular disease
physical activity
adverse drug
body mass index
risk factors
weight loss
weight gain