Three Separate Spike Antigen Exposures by COVID-19 Vaccination or SARS-CoV-2 Infection Elicit Strong Humoral Immune Responses in Healthcare Workers.
Thomas Theo BrehmFelix UllrichMichelle ThompsonJulia KüchenDorothee SchwingeAnthea SpierSamuel HuberJohannes Karl-Mark KnoblochMartin AepfelbacherMarylyn Martina AddoAnsgar W LohseMarc LütgehetmannJulian Schulze Zur-WieschPublished in: Vaccines (2022)
The current study indicates that three exposures to the viral spike protein by either SARS-CoV-2 infection or COVID-19 vaccination are necessary to elicit particularly strong humoral immune responses, which supports current vaccination recommendations.