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HPA Axis in Single- versus Divided-Dose Prednisolone for First Episode Nephrotic Syndrome: An Open Label RCT.

Tania KhanShakil AkhtarDevdeep MukherjeeSurupa BasuYincent TseRajiv Sinha
Published in: Clinical journal of the American Society of Nephrology : CJASN (2023)
Among children with first episode nephrotic syndrome, single and or divided dose prednisolone were equally effective in inducing remission with similar relapse rates, but single dose had less HPA suppression and longer time to first relapse.
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