The term "cancer" refers to the state in which cells in the body develop mutations and lose control over their replication. Malignant cancerous cells invade in various other tissue sites of the body. Chemotherapy, radiation, and surgery are the first-line modalities for the majority of solid cancers. These treatments work by mitigating the DNA damage of cancerous cells, but they can also cause harm to healthy cells. These side effects might be immediate or delayed, and they can cause a high rate of morbidity and mortality. Dietary interventions have a profound impact on whole-body metabolism, including immunometabolism and oncometabolism which have been shown to reduce cancer growth, progression, and metastasis in many different solid tumor models with promising outcomes in early phase clinical studies. Dietary interventions can improve oncologic or quality-of-life outcomes for patients that are undergoing chemotherapy or radiotherapy. In this chapter, we will focus on the impact of nutritional deficiencies, several dietary interventions and their proposed mechanisms which are used as a novel therapy in controlling and managing cancers.
Keyphrases
- induced apoptosis
- cell cycle arrest
- dna damage
- papillary thyroid
- oxidative stress
- prostate cancer
- squamous cell
- end stage renal disease
- endoplasmic reticulum stress
- minimally invasive
- cell death
- type diabetes
- locally advanced
- signaling pathway
- early stage
- newly diagnosed
- metabolic syndrome
- chronic kidney disease
- cell proliferation
- skeletal muscle
- intellectual disability
- childhood cancer
- acute coronary syndrome
- peritoneal dialysis
- lymph node metastasis
- pi k akt
- bone marrow
- mesenchymal stem cells
- patient reported outcomes
- autism spectrum disorder
- radiation induced
- dna repair
- coronary artery bypass
- cell therapy
- radical prostatectomy