Identification of complement factor H variants that predispose to pre-eclampsia: A genetic and functional study.

A Inkeri LokkiZ RenM TriebwasserE Dalynull nullM PerolaK AuroR BurwickJ E SalmonM DalyH LaivuoriJ P AtkinsonA JavaS Meri

Published in: BJOG : an international journal of obstetrics and gynaecology (2023)

These results suggest that complement dysregulation due to mutations in complement factor H is among the pathophysiological mechanisms underlying severe pre-eclampsia.

Keyphrases

copy number
gene expression
dna methylation
bioinformatics analysis