Dual Structural Design of Platinum-Nickel Hydrogels for Wearable Glucose Biosensing with Ultrahigh Stability.
Guanglei LiChenxin WangYao ChenFei LiuHaoxin FanBin YaoJia HaoYiting YuDan WenPublished in: Small (Weinheim an der Bergstrasse, Germany) (2023)
Wearable glucose sensors are of great significance and highly required in mobile health monitoring and management but suffering from limited long-term stability and wearable adaptability. Here a simultaneous component and structure engineering strategy is presented, which involves Pt with abundant Ni to achieve three-dimensional, dual-structural Pt-Ni hydrogels with interconnected networks of PtNi nanowires and Ni(OH) 2 nanosheets, showing prominent electrocatalytic activity and stability in glucose oxidation under neutral condition. Specifically, the PtNi (1:3) dual hydrogels shows 2.0 and 270.6 times' activity in the glucose electro-oxidation as much as the pure Pt and Ni hydrogels. Thanks to the high activity, structural stability, good flexibility, and self-healing property, the PtNi (1:3) dual gel-based non-enzymatic glucose sensing chip is endowed with high performance. It features a high sensitivity, an excellent selectivity and flexibility, and particularly an outstanding long-term stability over 2 months. Together with a pH sensor and a wireless circuit, an accurate, real-time, and remote monitoring of sweat glucose is achieved. This facile design of novel dual-structural metallic hydrogels sheds light to rationally develop new functional materials for high-performance wearable biosensors.
Keyphrases
- blood glucose
- drug delivery
- metal organic framework
- hyaluronic acid
- reduced graphene oxide
- extracellular matrix
- heart rate
- drug release
- wound healing
- tissue engineering
- hydrogen peroxide
- type diabetes
- blood pressure
- metabolic syndrome
- skeletal muscle
- quantum dots
- highly efficient
- high speed
- insulin resistance
- high throughput