Prognosis of spontaneous pneumomediastinum occurring in dermatomyositis or polymyositis patients with interstitial lung disease according to antimelanoma differentiation-associated gene 5 antibody status: a retrospective cohort study.

Kazuya AbeShunsuke FurutaYoshihisa KobayashiTakao SugiyamaShin-Ichiro Kagami Daiki Nakagomi Taro Iwamoto Kei Ikeda Hiroshi Nakajima

Published in: RMD open (2023)

SPNM occurred more frequently in anti-MDA5 antibody-positive than in anti-MDA5 antibody-negative myositis patients. SPNM occurrence was associated with higher mortality risk, especially in anti-MDA5 antibody-positive patients.

Keyphrases

interstitial lung disease
systemic sclerosis
end stage renal disease
ejection fraction
chronic kidney disease
rheumatoid arthritis
breast cancer cells
idiopathic pulmonary fibrosis
prognostic factors
risk assessment
copy number
transcription factor
cell proliferation
patient reported
pi k akt