Dissociable cognitive patterns related to depression and anxiety in multiple sclerosis.
Victoria M LeavittRachel BrandstadterMichelle FabianIlana Katz SandSylvia KlineovaStephen KriegerChristina LewisFred LublinAaron MillerGabrielle PelleKorhan BuyukturkogluPhillip L De JagerPeipei LiClaire S RileyAngeliki TsapanouJames F SumowskiPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2019)
Consistent mood-cognition relationships were identified in two independent cohorts of MS patients, suggesting that cognitive correlates of anxiety and depression are separable. This dissociation may support more precise models to inform treatment development. Treatment of mood symptoms may mitigate effects on cognition and/or treatment of cognition may mitigate effects on mood.