Pituitary apoplexy induced by gonadotropin-releasing hormone (GnRH) agonist administration for treatment of prostate cancer: a systematic review.

Rishi Raj Ghada Elshimy Aasems Jacob P V Akhila Arya Dileep C Unnikrishnan Riccardo CorreaZin W Myint

Published in: Journal of cancer research and clinical oncology (2021)

Although the use of GnRH agonists is relatively safe, it can rarely lead to pituitary apoplexy especially in patients with pre-existing pituitary adenoma. Physicians should be aware of this complication as it can be life threatening. A multidisciplinary team approach is recommended in treating individuals with pituitary apoplexy.

Keyphrases

prostate cancer
growth hormone
primary care
radical prostatectomy
palliative care
quality improvement
combination therapy