A new germacranolide from Ageratina vernalis.

Miguel Á Fuentes-FigueroaNeively Tlapale-LaraBeatriz Hernández-CarlosPedro Joseph-NathanEleuterio Burgueño-Tapia

Published in: Natural product research (2020)

The aerial parts of Ageratina vernalis provided the new germacranolide 1,10-epoxydeltoidin A (3), together with the known pentacyclic triterpenoid hopane-6α,22-diol (1), and the also known germacranolides deltoidin A (2) and 15-hydroxydeltoidin A (4). In addition, pTsOH catalyzed cyclization of 2 afforded the new guaianolide 5. The absolute configuration of 2, 4, and 5 was assigned by vibrational circular dichroism spectroscopy, while the complete 1H and 13C NMR data assignments of 2-5 followed from 1 D- and 2 D-NMR experiments.

Keyphrases

solid state
high resolution
magnetic resonance
electronic health record
room temperature
molecular dynamics simulations
density functional theory
single molecule
mass spectrometry
energy transfer
data analysis
deep learning
quantum dots