Epithelium-derived cystatin SN inhibits HDM protease activity in allergic asthma.

Lei YaoXijing YuanHeng FuQinxing GuoYunhui WuShurui XuanNazanin Zounemat KermaniIssssswan M AdcockXiaoning ZengYi LiuMin XieXin Yao

Published in: Allergy (2023)

Our data indicated that human CST1 protein suppresses asthma symptoms by protecting the asthmatic bronchial epithelial barrier through inhibiting allergenic protease activity. CST1 protein may serve as a potential biomarker for asthma control.

Keyphrases

lung function
allergic rhinitis
chronic obstructive pulmonary disease
signaling pathway
endothelial cells
air pollution
protein protein
cystic fibrosis
amino acid
physical activity
depressive symptoms
sleep quality
data analysis