Interaction between apolipoprotein E genotypes, excessive daytime sleepiness, and cognitive function in obstructive sleep apnea patients.
Fernanda Maurer BalthazarWalter André Dos Santos MoraesJames Richard HunterGilmar Fernandes do PradoLuciane Bizari Coin de CarvalhoPublished in: Arquivos de neuro-psiquiatria (2022)
Excessive daytime sleepiness and the ApoEε3/ε4 genotype are associated with worse cognitive performance in OSA patients. The combination of EDS and ε4 allele potentiates cognitive impairment.
Keyphrases
- obstructive sleep apnea
- end stage renal disease
- positive airway pressure
- ejection fraction
- newly diagnosed
- chronic kidney disease
- sleep quality
- cognitive impairment
- prognostic factors
- peritoneal dialysis
- sleep apnea
- type diabetes
- patient reported outcomes
- high fat diet
- physical activity
- depressive symptoms
- weight loss
- insulin resistance