Therapeutic enhancement of blood-brain and blood-tumor barriers permeability by laser interstitial thermal therapy.

Afshin SalehiMounica R PaturuBhuvic PatelMatthew D CainTatenda MahlokozeraAlicia B YangTsen-Hsuan LinEric C LeuthardtHiroko YanoSheng-Kwei SongRobyn S KleinRobert SchmidtAlbert H Kim

Published in: Neuro-oncology advances (2020)

Together, these results suggest that LITT can locally disrupt the BBB and BTB, enabling the targeted delivery of systemic therapies, including, potentially, antibody-based agents.

Keyphrases

blood brain barrier
resting state
endothelial cells
stem cells
functional connectivity
cerebral ischemia
mass spectrometry
bone marrow
high resolution